Review paper
Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity
Abstract
Retinal disease is one of the most active areas of gene therapy, with clinical trials ongoing in the United States for five diseases. There are currently no treatments for patients with late-stage disease in which photoreceptors have been lost. Optogenetic gene therapies are in development, but, to date, have suffered from the low light sensitivity of microbial opsins, such as channelrhodopsin and halorhodopsin, and azobenzene-based...
Paper Details
Title
Optogenetic Vision Restoration Using Rhodopsin for Enhanced Sensitivity
Published Date
Oct 1, 2015
Journal
Volume
23
Issue
10
Pages
1562 - 1571
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History