N-cadherin impedes proliferation of the multiple myeloma cancer stem cells.
Abstract
Multiple myeloma (MM) is an incurable malignancy of the plasma cells localized to the bone marrow. A rare population of MM cancer stem cells (MM-CSCs) has been shown to be responsible for maintaining the pull of residual disease and to contribute to myeloma relapse. The stem cells are found in a bone marrow niche in contact with the stromal cells that are responsible for maintaining the proliferative quiescence of the MM-CSC and regulate its...
Paper Details
Title
N-cadherin impedes proliferation of the multiple myeloma cancer stem cells.
Published Date
Jan 1, 2013
Journal
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