Preparation and characterization of spray dried complexes of lutein with cyclodextrins

Lutein (LUT) is one of the most important carotenoid and; the most prominent being its antioxidant activity. However, its use is limited due to poor solubility and instability under adverse conditions. An attempt is made to increase the solubility and hence bioavailability of LUT using various cyclodextrins viz., betacyclodextrin (βCD), hydroxypropyl betacyclodextrin (HP-βCD) and methyl betacyclodextrin (M-βCD). Physical mixtures and spray dried...