Pregnancy-associated cardiomyopathy in survivors of childhood cancer.

Published on Feb 1, 2016in Journal of Cancer Survivorship4.442
· DOI :10.1007/S11764-015-0457-8
Melissa R. Hines1
Estimated H-index: 1
(UNC: University of North Carolina at Chapel Hill),
Daniel A. Mulrooney35
Estimated H-index: 35
(UTHSC: University of Tennessee Health Science Center)
+ 5 AuthorsMonika L. Metzger38
Estimated H-index: 38
(UTHSC: University of Tennessee Health Science Center)
Purpose Current information regarding pregnancy-associated cardiomyopathy among women treated for childhood cancer is insufficient to appropriately guide counseling and patient management. This study aims to characterize its prevalence within a large cohort of females exposed to cardiotoxic therapy.
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To varying extents, women with pre-existing cardiomyopathies have a limited cardiovascular reserve. The hemodynamic challenges of pregnancy, labor, and delivery pose unique risks to this group of patients, which can result in clinical decompensation with overt heart failure, arrhythmias, and rarely, maternal death. A multidisciplinary team approach and a controlled delivery are crucial to adequate management of patients with underlying heart disease. Pre-conception planning and risk assessment a...
With the improvement in survival from childhood cancer, late effects of therapy are becoming more apparent. Cardiac disease, one of these late effects, has a significant impact on the life of survivors of childhood cancers. Most survivors are followed by primary care doctors and adult subspecialists after they have graduated from pediatric centers. Since much of the cardiac toxicity of therapy occurs years off of therapy, it is important for these physicians to be aware of how to monitor survivo...
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