Chemistry

Distilled water

Chromatography

Traditional medicine

Obesity

Weight loss

Endocrinology

Body weight

Momordica

Lipid profile

Internal medicine

Medicine

Cholesterol

Overweight

PubMed

A steady weight increase disproportionate to height is by far the most prevalent type of body weight imbalance (overweight and obesity) in apparently healthy individuals of growing age. Many subsisting weight-reduction regimes or formulations are ineffective. Therefore, an effective and affordable weight-reduction product will add to the options available for the management of weight-related conditions.This study aimed to investigate the effects of graded oral doses of methanolic seed extract of Momordica charantia (MC) on the body weights and cholesterol levels of male rats.Twenty adult male Sprague-Dawley rats, weighing 176 +/- 70 g, were used for this study. The animals, divided randomly into 4 groups (A-D) received daily graded oral doses of 15, 25 and 50 mg/100 g body weight of methanolic seed extract of MC, respectively, while Group D rats had distilled water for 56 days. The weights of the animals in each group were recorded weekly throughout the duration of the experiment. Serum cholesterol levels wer...

Effect of methanolic seed extract of Momordica charantia on body weight and serum cholesterol level of male Sprague-Dawley rats.