Biology

Angiogenesis

Hemostasis

Endocrinology

Immunology

Bioinformatics

Adipokine

Insulin resistance

Inflammation

Internal medicine

Medicine

Obesity

Adipose tissue

International Journal of Molecular Sciences

Adipokines are currently widely studied cellular signaling proteins produced by adipose tissue and involved in various processes, including inflammation; energy and appetite modulation; lipid and glucose metabolism; insulin sensitivity; endothelial cell functioning; angiogenesis; the regulation of blood pressure; and hemostasis. The current review attempted to highlight the key functions of adipokines in the inflammatory mechanisms of obesity, its complications, and its associated diseases. An extensive search for materials on the role of adipokines in the pathogenesis of obesity was conducted online using the PubMed and Scopus databases until October 2022.

The Role of Adipokines in Inflammatory Mechanisms of Obesity