Review paper
Mitochondria and cell death-associated inflammation
Abstract
Mitochondria have recently emerged as key drivers of inflammation associated with cell death. Many of the pro-inflammatory pathways activated during cell death occur upon mitochondrial outer membrane permeabilization (MOMP), the pivotal commitment point to cell death during mitochondrial apoptosis. Permeabilised mitochondria trigger inflammation, in part, through the release of mitochondrial-derived damage-associated molecular patterns (DAMPs)....
Paper Details
Title
Mitochondria and cell death-associated inflammation
Published Date
Nov 29, 2022
Volume
30
Issue
2
Pages
304 - 312