Review paper
Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
Abstract
Exosomes are well-known key mediators of intercellular communication and contribute to various physiological and pathological processes. Their biogenesis involves four key steps, including cargo sorting, MVB formation and maturation, transport of MVBs, and MVB fusion with the plasma membrane. Each process is modulated through the competition or coordination of multiple mechanisms, whereby diverse repertoires of molecular cargos are sorted into...
Paper Details
Title
Exosome biogenesis: machinery, regulation, and therapeutic implications in cancer
Published Date
Nov 1, 2022
Journal
Volume
21
Issue
1