Binge eating

Receptor

Binge-eating disorder

Psychiatry

Eating disorders

Placebo

Smoking cessation

Alternative medicine

Psychology

Internal medicine

Bupropion

Antagonist

Medicine

Bulimia nervosa

Naltrexone

Randomized controlled trial

Pathology

American Journal of Psychiatry

Binge-eating disorder, the most prevalent eating disorder, is a serious public health problem associated with obesity, psychiatric and medical comorbidities, and functional impairments. Binge-eating disorder remains underrecognized and infrequently treated, and few evidence-based treatments exist. The authors tested the effectiveness of naltrexone-bupropion and behavioral weight loss therapy (BWL), alone and combined, for binge-eating disorder comorbid with obesity.

Naltrexone-Bupropion and Behavior Therapy, Alone and Combined, for Binge-Eating Disorder: Randomized Double-Blind Placebo-Controlled Trial