The family <i>Hepeviridae</i> includes enterically transmitted small quasi-enveloped or non-enveloped positive-sense single-stranded RNA viruses infecting mammals and birds (subfamily <i>Orthohepevirinae</i>) or fish (<i>Parahepevirinae</i>). Hepatitis E virus (genus <i>Paslahepevirus</i>) is responsible for self-limiting acute hepatitis in humans; the infection may become chronic in immunocompromised individuals and extrahepatic manifestations have been described. Avian hepatitis E virus (genus <i>Avihepevirus</i>) causes hepatitis-splenomegaly syndrome in chickens. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family <i>Hepeviridae</i>, which is available at www.ictv.global/report/hepeviridae.