The high harvest losses associated with the mechanical harvesting of maize in China are currently a major barrier to the adoption of this technology. This paper summarizes works of literature regarding harvest losses from the combine harvesting of maize in China and abroad. The main findings are as follows: (1) In 2012-2019, 2987 samples data obtained from the major maize production areas of China showed that the average harvest loss was 345.2 kg/hm2 (3.5% of the average yield), with losses ranging from 0 to 9288.5 kg/hm2; (2) The harvest losses from combine harvesting are mainly caused by the dropping of ears. The ear losses include the pre-harvest loss caused by ear abscission, damage caused by maize borer, lodging, and the ear loss during combine harvesting, and the main pre-harvest loss is caused by lodging; (3) Harvest losses are affected by maize variety, planting mode, cultivation management, pests and diseases, weather conditions during harvesting, harvest date, combine harvester type, harvester adjustment, operator proficiency, and the terrain conditions of the maize field; (4) The harvest losses from combine harvesting are also related to the type of header, feeding and threshing methods, the adjustment of header stripping clearance, feeding amount, forward speed, cylinder or rotor speed, and the clearance between the cylinder and the concave of the harvester. However, the combine losses mainly come from header losses. In order to reduce the harvest losses, the following solutions were proposed: (1) Breed and select maize varieties which are resistant to lodging, especially during the field drying of mature grains, as well as those resistant to maize borer and stalk rot; (2) Select varieties suitable for grain harvest—which requires matching the accumulated-temperature demand of the maize hybrids, optimal plant density, row spacing, and irrigation and fertilizer management with the light and heat conditions of the production area while cultivating uniform populations and healthy plants—as well as preven...