Internal medicine

Stroke (engine)

Bolus (digestion)

Myocardial infarction

Ischemia

Engineering

Surgery

Tissue plasminogen activator

Tenecteplase

Thrombolysis

Modified Rankin Scale

Fibrinolytic agent

Ischemic stroke

Anesthesia

Clinical trial

Medicine

Mechanical engineering

The Lancet Neurology

Treatment with tenecteplase on the MSU in Melbourne resulted in a superior rate of early reperfusion compared with alteplase, and no safety concerns were noted. This trial provides evidence to support the use of tenecteplase and MSUs in an optimal model of stroke care.

Comparison of tenecteplase with alteplase for the early treatment of ischaemic stroke in the Melbourne Mobile Stroke Unit (TASTE-A): a phase 2, randomised, open-label trial