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Original paper

Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage

Volume: 19, Issue: 1, Pages: 75 - 91
Published: Apr 26, 2022
Abstract
Aminoglycosides exhibit ototoxicity by damaging mitochondria, which in turn generate reactive oxygen species that induce hair cell death and subsequent hearing loss. It is well known that damaged mitochondria are degraded by mitophagy, an important mitochondrial quality control system that maintains mitochondrial homeostasis and ensures cell survival. However, it is unclear whether dysregulation of mitophagy contributes to aminoglycoside-induced...
Paper Details
Title
Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage
Published Date
Apr 26, 2022
Journal
Volume
19
Issue
1
Pages
75 - 91
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