Immunotherapy

Cancer immunotherapy

Effector

Biology

Germination

Cancer

Interleukin 21

Cytotoxic T cell

In vitro

Immunology

T cell

Natural killer cell

Botany

Lymphokine-activated killer cell

Cell biology

Cancer research

Genetics

Biochemistry

Priming (agriculture)

Immune system

Cancer cell

Cell

NK cells are an attractive option for cell-based therapy but require optimization. BH3 mimetics chosen by BH3 profiling synergized with NK cell therapy to enhance cancer-cell killing by NK cells in an approach that could also be used for other cell therapy platforms.

Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis