Gene

Stenotrophomonas maltophilia

Stenotrophomonas

Gram-negative bacterial infections

Intensive care medicine

Pseudomonas

Pseudomonas aeruginosa

Bacteria

Biology

Pathogen

Antibiotic resistance

Genetics

Antibiotics

Microbiology

Opportunistic pathogen

Medicine

Multiple drug resistance

Virulence

JAC-Antimicrobial Resistance

Stenotrophomonas maltophilia is a non-fermenting, Gram-negative bacillus that has emerged as an opportunistic nosocomial pathogen. Its intrinsic multidrug resistance makes treating infections caused by S. maltophilia a great clinical challenge. Clinical management is further complicated by its molecular heterogeneity that is reflected in the uneven distribution of antibiotic resistance and virulence determinants among different strains, the shortcomings of available antimicrobial susceptibility tests and the lack of standardized breakpoints for the handful of antibiotics with in vitro activity against this microorganism. Herein, we provide an update on the most recent literature concerning these issues, emphasizing the impact they have on clinical management of S. maltophilia infections.

Clinical challenges treating<i>Stenotrophomonas maltophilia</i>infections: an update

Clinical challenges treatingStenotrophomonas maltophiliainfections: an update