Internal medicine

Adverse effect

Disease

Dialysis

Immunogenicity

Population

Coronavirus disease 2019 (COVID-19)

Infectious disease (medical specialty)

Pandemic

Vaccination

Immunology

Immunity

Medicine

Immune system

Environmental health

Kidney International

The COVID-19 pandemic has profound adverse effects on the population on dialysis. Patients requiring dialysis are at an increased risk of SARS-CoV-2 infection and mortality, and many have experienced psychological distress as well as delayed or suboptimal care. COVID-19 survivors have prolonged viral shedding, but generally develop a robust and long-lasting humoral immune response that correlates with initial disease severity. However, protection against reinfection is incomplete. A growing body of evidence reveals delayed and blunted immune responses to SARS-CoV-2 vaccination.

COVID-19 in dialysis: clinical impact, immune response, prevention, and treatment