The long road to leptin

Volume: 126, Issue: 12, Pages: 4727 - 4734
Published: Dec 1, 2016
Abstract
Leptin is an adipose tissue hormone that functions as an afferent signal in a negative feedback loop that maintains homeostatic control of adipose tissue mass. This endocrine system thus serves a critical evolutionary function by protecting individuals from the risks associated with being too thin (starvation) or too obese (predation and temperature dysregulation). Mutations in leptin or its receptor cause massive obesity in mice and humans, and...
Paper Details
Title
The long road to leptin
Published Date
Dec 1, 2016
Volume
126
Issue
12
Pages
4727 - 4734
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