Hallux valgus is a foot pathological condition showing a lateral deviation of the first phalange and medial deviation of the first metatarsal. The purpose of the current study was to evaluate a longitudinal effect of minimalist footwear running protocol for a mild/moderate hallux valgus patient. The computer tomography (CT) images from a male hallux valgus (HV) patient were respectively scanned pre and post 12-week minimalist footwear running intervention. The pre and post -intervention foot finite element (FE) models were developed from the foot three-dimensional geometries manually segmented via the MIMICS 21.0. The post-process with SolidWorks 2019 was conducted for model assembly, consisting of 24 bones, 22 cartilages, five plantar fascia , and lumped encapsulated soft tissue. The foot FE models were solved in ANSYS Workbench 2020 R1 package. The FE models were validated against the plantar pressure ( pre : 0.146 MPa vs 0.155 MPa, and post : 0.156 MPa vs 0.17 MPa) and vertical displacements ( pre : 2.6 mm vs 2.4 ± 0.4 mm, and post 1.1 mm vs 1.3 ± 0.4 mm) of navicular measured from experiments. The first metatarsophalangeal joint showed varus realignment and the von Mises stress in the first metatarsal and the second metatarsal decreased 72.1% and 51.2% compared with pre-intervention (M1: 4.41 MPa and M2: 4.18 MPa). This framework investigated the shape adjustment and functional recovery in the mild/moderate HV deformity , which may provide references and implications for future studies with a larger cohort.