Original paper
Wedelolactone and coumestan derivatives as new antihepatotoxic and antiphlogistic principles.
Abstract
For the study of structure-activity relationships, the antihepatotoxic wedelolactone (7-methoxy-5,11,12-trihydroxy-coumestan) and 6 coumestan derivatives were synthesized by the application of a modified method of Wanzlich. An evaluation of the biological characteristics of the synthetic compounds and acuminatin from Musa acuminata showed that most of the wedelolactone derivatives significantly protected primary cultured liver cells from the...
Paper Details
Title
Wedelolactone and coumestan derivatives as new antihepatotoxic and antiphlogistic principles.
Published Date
May 1, 1988
Journal
Volume
38
Issue
5
Pages
661 - 5
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Notes
History