Original paper
Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel
Abstract
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies worldwide. Both genetic and epigenetic changes are involved in esophageal carcinogenesis. CHFR methylation has been found frequently in different cancers and is regarded as a marker of taxane sensitivity. CHFR methylation was found in 0% (0/16) of normal mucosa, 2.9% (1/34) of grade I dysplasia, 0% (0/8) of grade II dysplasia, 12.5% (1/8) of grade III dysplasia and...
Paper Details
Title
Methylation of CHFR sensitizes esophageal squamous cell cancer to docetaxel and paclitaxel
Published Date
Dec 31, 2014
Journal
Volume
6
Issue
1-2
Pages
38 - 48
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Notes
History