Abscisic acid inhibited reactive oxygen species‐mediated endoplasmic reticulum stress by regulating the PPAR‐γ signaling pathway in ARDS mice

Volume: 35, Issue: 12, Pages: 7027 - 7038
Published: Nov 17, 2021
Abstract
Acute respiratory distress syndrome (ARDS) is a life‐threatening form of a respiratory disorder, and there are few effective therapies. Abscisic acid (ABA) has been proven to be effective in influenza and asthma. Herein, we explored the protective effect of ABA on the resolution of ARDS and the underlying mechanism. Mice were challenged with lipopolysaccharide (LPS) to establish an ARDS model. We found that ABA reduced pulmonary injury, with...
Paper Details
Title
Abscisic acid inhibited reactive oxygen species‐mediated endoplasmic reticulum stress by regulating the PPAR‐γ signaling pathway in ARDS mice
Published Date
Nov 17, 2021
Volume
35
Issue
12
Pages
7027 - 7038
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