Original paper
Lamin C is required to establish genome organization after mitosis
Abstract
Background The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery. Evidence suggests that lamins A and C are the predominant lamins involved in the peripheral association of LADs, potentially serving different roles. Results Here, we examine chromosome architecture in mouse cells...
Paper Details
Title
Lamin C is required to establish genome organization after mitosis
Published Date
Nov 15, 2021
Journal
Volume
22
Issue
1
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Notes
History