Stool microbiota are superior to saliva in distinguishing cirrhosis and hepatic encephalopathy using machine learning

Saliva and stool microbiota are altered in cirrhosis. Since stool is logistically difficult to collect compared to saliva, it is important to determine their relative diagnostic and prognostic capabilities. We aimed to determine the ability of stool vs. saliva microbiota to differentiate between groups based on disease severity using machine learning (ML).Controls and outpatients with cirrhosis underwent saliva and stool microbiome analysis....