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Original paper

A one-step synthesis of substituted benzo- and pyridine-fused 1H-imidazoles

Volume: 52, Issue: 1, Pages: 96 - 105
Published: Nov 17, 2021
Abstract
Substituted benzimidazoles and pyrimidazoles are an important group of heterocyclic aromatic organic compounds in the field of medicinal chemistry. A one-step microwave accelerated synthesis of substituted benzo- and pyridine-fused 1H-imidazoles has been described. Mechanistically, the reaction proceeds by reacting substituted 2-fluoronitrobenzene and substituted arylamine through the formation of N-hydroxy intermediate, which at higher...
Paper Details
Title
A one-step synthesis of substituted benzo- and pyridine-fused 1H-imidazoles
Published Date
Nov 17, 2021
Volume
52
Issue
1
Pages
96 - 105
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