Biological function and molecular mechanism of SRSF3 in cancer and beyond (Review)
Abstract
Serine/arginine-rich splicing factor 3 (SRSF3; also known as SRp20), an important member of the family of SRSFs, is abnormally expressed in tumors, resulting in aberrant splicing of hub genes, such as CD44, HER2, MDM4, Rac family small GTPase 1 and tumor protein p53. Under normal conditions, the splicing and expression of SRSF3 are strictly regulated. However, the splicing, expression and phosphorylation of SRSF3 are abnormal in tumors. SRSF3...
Paper Details
Title
Biological function and molecular mechanism of SRSF3 in cancer and beyond (Review)
Published Date
Nov 16, 2021
Journal
Volume
23
Issue
1
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