Risk of type 2 diabetes mellitus and cardiovascular complications in KCNJ11, HHEX and SLC30A8 genetic polymorphisms carriers: A case-control study

Tutun Das Aka; Urmi Saha; Sayara Akter Shati; Md. Abdul Aziz; Mobashera Begum; Md. Saddam Hussain; Md. Shalahuddin Millat; Mohammad Sarowar Uddin; Mohammad Safiqul Islam

doi:https://doi.org/10.1016/j.heliyon.2021.e08376

doi.org/10.1016/j.heliyon.2021.e08376

Risk of type 2 diabetes mellitus and cardiovascular complications in KCNJ11, HHEX and SLC30A8 genetic polymorphisms carriers: A case-control study

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..., Mohammad Safiqul Islam

20

Heliyon4.00

Volume: 7, Issue: 11, Pages: e08376 - e08376

Published: Nov 1, 2021

Abstract

Type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) are two deadly diseases caused by the complex interaction of multiple genetic loci, lifestyle and environmental factors. Genome-wide association studies described hundreds of susceptibility loci for T2DM and T2DM-related CVD, but it remains uncertain due to geographic and ethnic variations. The objective of this study was to evaluate the associations of KCNJ11 rs5219, SLC30A8...

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Paper Details

Title

Risk of type 2 diabetes mellitus and cardiovascular complications in KCNJ11, HHEX and SLC30A8 genetic polymorphisms carriers: A case-control study

DOI

doi.org/10.1016/j.heliyon.2021.e08376

Published Date

Nov 1, 2021

Journal

Heliyon

Volume

7

Issue

11

Pages

e08376 - e08376

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