12 Myocardial inflammation and diffuse fibrosis underpin the electrophysiological derangements of the ageing human heart–A CMR-ECGI study

Background

Susceptibility to malignant ventricular arrhythmias can be predicted by activation recovery interval (ARI) and repolarisation time (RT) biomarkers noninvasively derived by electrocardiographic imaging (ECGI). The interaction between cardiac structural and electrophysiological changes during aging is unclear. We used our recently developed cardiovascular magnetic resonance (CMR)-ECGI vest to understand how the ageing...