3D Image Super-Resolution by Fluorophore Fluctuations and MA-TIRF Microscopy Reconstruction (3D-COL0RME)

We propose a 3D super-resolution approach to improve both lateral and axial spatial resolution of a thin layer adjacent to the coverslip in Total Internal Reflection Fluorescence (TIRF) imaging applications. Our approach, called 3D-COL0RME (3D - Covariance-based ℓ 0 super-Resolution Microscopy with intensity Estimation) improves both lateral and...