Original paper
Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity
Abstract
Peritoneal immune cells reside unanchored within the peritoneal fluid in homeostasis. Here, we examined the mechanisms that control bacterial infection in the peritoneum using a mouse model of abdominal sepsis following intraperitoneal Escherichia coli infection. Whole-mount immunofluorescence and confocal microscopy of the peritoneal wall and omentum revealed that large peritoneal macrophages (LPMs) rapidly cleared bacteria and adhered to the...
Paper Details
Title
Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity
Published Date
Nov 1, 2021
Journal
Volume
54
Issue
11
Pages
2578 - 2594.e5
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Notes
History