Original paper

Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity

Volume: 54, Issue: 11, Pages: 2578 - 2594.e5
Published: Nov 1, 2021
Abstract
Peritoneal immune cells reside unanchored within the peritoneal fluid in homeostasis. Here, we examined the mechanisms that control bacterial infection in the peritoneum using a mouse model of abdominal sepsis following intraperitoneal Escherichia coli infection. Whole-mount immunofluorescence and confocal microscopy of the peritoneal wall and omentum revealed that large peritoneal macrophages (LPMs) rapidly cleared bacteria and adhered to the...
Paper Details
Title
Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity
Published Date
Nov 1, 2021
Journal
Volume
54
Issue
11
Pages
2578 - 2594.e5
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