Distinct structural and dynamic components of portal hypertension in different animal models and human liver disease etiologies
Abstract
Liver fibrosis is the static and main (70%-80%) component of portal hypertension (PH). We investigated dynamic components of PH by a three-dimensional analysis based on correlation of hepatic collagen proportionate area (CPA) with portal pressure (PP) in animals or HVPG in patients.Different animal models (bile duct ligation: n = 31, carbon tetrachloride: n = 12, thioacetamide: n = 12, choline-deficient high-fat diet: n = 12) and patients with a...
Paper Details
Title
Distinct structural and dynamic components of portal hypertension in different animal models and human liver disease etiologies
Published Date
Dec 20, 2021
Journal
Volume
75
Issue
3
Pages
610 - 622
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