Defibrotide for Sinusoidal Obstruction Syndrome and Nodular Regenerative Hyperplasia After Oxaliplatin-Based Hepatic Intra-Arterial Chemotherapy: A Case Report

•Sinusoidal obstruction syndrome (SOS) is a life-threatening complication of oxaliplatin-based chemotherapy. •Nodular regenerative hyperplasia can be associated at a late stage of SOS, and should be suspected in case of signs of portal hypertension such as thrombocytopenia or splenomegaly. •To our knowledge, this is the first report of SOS occurring after oxaliplatin hepatic arterial infusion (HAI). •We report a case of a 43-year-old man, with...