Predicting fluid-response, the heart of hemodynamic management: A model-based solution

Intravenous fluid infusions are an important therapy for patients with circulatory shock. However, it is challenging to predict how patients’ cardiac stroke volume (SV) will respond, and thus identify how much fluids should be delivered, if any. Model-predicted SV time-profiles of response to fluid infusions could potentially be used to guide fluid therapy. A clinically applicable model-based method predicts SV changes in response to...