Engineering

Surgery

Exoskeleton

Balance (ability)

Treadmill

VO2 max

Heart rate

Radiology

Mechanical engineering

Gait

Preferred walking speed

Blood pressure

Physical therapy

Structural engineering

Medicine

Physical medicine and rehabilitation

Limiting

Amputation

Running economy

Backpack

Nature Medicine

Above-knee amputation severely reduces the mobility and quality of life of millions of individuals. Walking with available leg prostheses is highly inefficient, and poor walking economy is a major problem limiting mobility. Here we show that an autonomous powered hip exoskeleton assisting the residual limb significantly improves metabolic walking economy by 15.6 ± 2.9% (mean ± s.e.m.; two-tailed paired t-test, P = 0.002) in six individuals with above-knee amputation walking on a treadmill. The observed metabolic cost improvement is equivalent to removing a 12-kg backpack from a nonamputee individual. All participants were able to walk overground with the exoskeleton, including starting and stopping, without notable changes in gait balance or stability. This study shows that assistance of the user’s residual limb with a powered hip exoskeleton is a viable solution for improving amputee walking economy. By significantly reducing the metabolic cost of walking, the proposed hip exoskeleton may have a considerable positive impact on mobility, improving the quality of life of individuals with above-knee amputations. In individuals with above-knee amputation, a powered hip exoskeleton, which reduces the metabolic cost of walking by adding energy at the hip joint, greatly improves walking economy and has the potential to improve mobility.

Powered hip exoskeleton improves walking economy in individuals with above-knee amputation