Original paper

Cytokine release syndrome after CAR infusion in pediatric patients with refractory/relapsed B-ALL: is there a role for diclofenac?

Volume: 108, Issue: 6, Pages: 556 - 562
Published: Oct 21, 2021
Abstract
Cytokine release syndrome (CRS) is a major complication after chimeric-antigen receptor T-cell treatment, characterized by an uncontrolled systemic inflammatory reaction. We investigated the potential role of diclofenac in the management of CRS in five pediatric patients treated for relapsed/refractory B-lineage acute lymphoblastic leukemia.In case of persistent fever with fever-free intervals shorter than 3 hours, diclofenac continuous infusion...
Paper Details
Title
Cytokine release syndrome after CAR infusion in pediatric patients with refractory/relapsed B-ALL: is there a role for diclofenac?
Published Date
Oct 21, 2021
Volume
108
Issue
6
Pages
556 - 562
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