Deep eutectic liquid as transdermal delivery vehicle of Risperidone

The work outlined herein describes an evaluation of a green solvent working as a drug solubility and penetration enhancer made up of a deep eutectic system (DES) composed of menthol (MN) and capric acid (CA). Risperidone (RIS) was tested as a class II model drug. The system efficacy in enhancing drug solubility was carried out at five different CA: MN mass ratios (w/w) of 7:3, 6:4, 5:5, 4:6, and 3:7. The 7:3 CA:MN (w/w) mass showed the most...