Qualitative and quantitative assessment of oxidative stress in human living erythrocytes using two-photonmicroscopy imaging technique

Red blood cells (RBCs) are unceasingly exposed to exogenous reactive oxygen species (ROS) during their passage through the circulatory system. Nevertheless, RBCs have a large antioxidant system including ascorbate, vitamin E, catalase, superoxide dismutase, ergothioneine, glutathione, glutathione peroxidase and peroxiredoxin, which are assumed to eliminate ROS. The purpose of this study is to design a new effective method for evaluation of...