A commentary on “The role of rapid intraoperative parathyroid hormone (ioPTH) assay in determining outcome of parathyroidectomy in primary hyperparathyroidism: A systematic review and meta-analysis” (Int J Surg 2021; 92:106042)

Dear Editor, Primary hyperparathyroidism (PHPT) is a disease caused by intrinsic increase in parathyroid cell activity accompanied by excessive parathyroid hormone (PTH) secretion and subsequent modifications of calcium and bone metabolism [1]. PHPT has a higher incidence than previously thought, because many patients are diagnosed with mild, paucisymptomatic or even asymptomatic forms of the disease on routine calcium measurement, evaluation of...