Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential
Volume: 50, Pages: 116453 - 116453
Published: Nov 1, 2021
Abstract
A series of novel indole-azolidinone hybrids has been synthesized via Knoevenagel reaction of 5-fluoro-3-formyl-1H-indole-2-carboxylic acid methyl ester and some azolidinones differing in heteroatoms in positions 1, 2 and 4. Their anticancer activity in vitro was screened towards MCF-7 (breast cancer), HCT116 (colon cancer), HepG2 (hepatoma), HeLa (cervical cancer), A549 (lung cancer), WM793 (melanoma) and THP-1 (leukemia) cell lines, and a...
Paper Details
Title
Synthesis of novel indole-thiazolidinone hybrid structures as promising scaffold with anticancer potential
Published Date
Nov 1, 2021
Volume
50
Pages
116453 - 116453
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