The release of abuse-deterrent OxyContin and adolescent heroin use

To determine the association between the abuse-deterrent reformulation of OxyContin and adolescent lifetime heroin use in the United States.The quasi-experimental study uses individual survey data from the 1999-2019 Youth Risk Behavior Surveillance System to examine whether the reformulation of OxyContin in August 2010 affected adolescent lifetime heroin use, exploiting heterogeneity in state-level rates of OxyContin misuse before the...