Gene

Biology

Colorectal cancer

T cell

CCL5

Immunology

Genetics

Bioinformatics

Immune system

Internal medicine

IL-2 receptor

Oncology

Medicine

Gene expression profiling

Cancer

Gene expression

Annals of Oncology

The CCR5/CCL5 axis plays a key role in CRC. We previously showed that polymorphisms in CCR5/CCL5 are associated with outcome in patients (pts) with metastatic CRC. Here we aimed to characterize the molecular features associated with CCR5/CCL5 expression in CRC and whether CCR5/CCL5 levels could impact treatment outcome.

454P CCR5/CCL5 gene expression in colorectal cancer (CRC): Comprehensive profiling and clinical value