Original paper
Biomaterial-enabled induction of pancreatic-specific regulatory T cells through distinct signal transduction pathways
Volume: 11, Issue: 6, Pages: 2468 - 2481
Published: Oct 5, 2021
Abstract
Autoimmune diseases-where the immune system mistakenly targets self-tissue-remain hindered by non-specific therapies. For example, even molecularly specific monoclonal antibodies fail to distinguish between healthy cells and self-reactive cells. An experimental therapeutic approach involves delivery of self-molecules targeted by autoimmunity, along with immune modulatory signals to produce regulatory T cells (TREG) that selectively stop attack...
Paper Details
Title
Biomaterial-enabled induction of pancreatic-specific regulatory T cells through distinct signal transduction pathways
Published Date
Oct 5, 2021
Volume
11
Issue
6
Pages
2468 - 2481
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Notes
History