Uptake of nicotinic acetylcholine receptor imaging agent is reduced in the pro-inflammatory macrophage
Abstract
Macrophages play a vital role in the development of atherosclerotic cardiovascular disease. Macrophages are functionally and phenotypically heterogeneous immune cells and commonly exist in two distinct or polarized subsets: pro-inflammatory M1 and anti-inflammatory M2 phenotypes. Previous reports suggest that stimulation of α7 or α4β2 nicotinic acetylcholine receptors (nAChRs) in macrophages leads to an anti-inflammatory response. However, the...
Paper Details
Title
Uptake of nicotinic acetylcholine receptor imaging agent is reduced in the pro-inflammatory macrophage
Published Date
Nov 1, 2021
Journal
Volume
102-103
Pages
45 - 55
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