Biphasic nanofibrous scaffolds based on collagen and PLC for controlled release LL‐37 in guided bone regeneration

This is a feasibility study on the ability of biodegradable collagen coated with poly(L‐lactide‐ co ‐ ε ‐caprolactone) (PLC) to deliver the antimicrobial peptide, LL‐37, for usage as a barrier membrane in guided bone regeneration. In this study, a nanofibrous PLC is fabricated using the electrospinning technique to establish the controlled release of the LL‐37, which adsorbed onto collagen scaffold (LL/Col), in order to produce a LL/Col/PLC...