Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring—the heart as a target for fetal programming in rats
Abstract
The impact of diabetic pregnancy has been investigated extensively regarding offspring metabolism; however, little is known about the influence on the heart. We aimed to characterise the effects of a diabetic pregnancy on male adult offspring cardiac health after feeding a high-fat diet in an established transgenic rat model.We applied our rat model for maternal type 2 diabetes characterised by maternal insulin resistance with hyperglycaemia and...
Paper Details
Title
Diabetic pregnancy as a novel risk factor for cardiac dysfunction in the offspring—the heart as a target for fetal programming in rats
Published Date
Sep 18, 2021
Journal
Volume
64
Issue
12
Pages
2829 - 2842
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History