The role of hepatic lipid composition in obesity‐related metabolic disease

Obesity is a primary antecedent to non‐alcoholic fatty liver disease whose cardinal feature is excessive hepatic lipid accumulation. Although total hepatic lipid content closely associates with hepatic and systemic metabolic dysfunction, accumulating evidence suggests that the composition of hepatic lipids may be more discriminatory. This review summarises cross‐sectional human studies using liver biopsy/lipidomics and proton magnetic resonance...