Multiple myeloma with concurrent herpes zoster ophthalmicus: a case report.

Published on Sep 20, 2021in Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie1.882
· DOI :10.1016/J.JCJO.2021.08.016
Zoya Chaudhry (McGill University), K. M. Oliver1
Estimated H-index: 1
(McGill University),
John Galic1
Estimated H-index: 1
(McGill University)
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Abstract Background Genetic variations have been identified in the genome of varicella-zoster virus (VZV) strains using vesicle fluid, varicella scabs and throat swab samples. We report a rare case of VZV-associated uveitis with severe hyphema, which was immediately diagnosed by polymerase chain reaction (PCR) using the aqueous humor, in which we were able to analyze the VZV genotype for the first time. Case presentation A 16-year-old Japanese boy was referred to our hospital with a 20-day histo...
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PURPOSE: To report a case of bilateral central retinal vein occlusion as the presenting feature of new onset multiple myeloma in an otherwise healthy man. METHODS: A 44-year-old man presented with painless visual changes in his left eye. Ophthalmic examination revealed what appeared to be bilateral central retinal vein occlusion and hematologic assessment resulted in the diagnosis of immunoglobulin G multiple myeloma. RESULTS: Initial management was plasma exchange followed by a chemotherapy reg...
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Aim: To investigative whether clinical manifestations of anterior uveitis are associated with the viral load of varicella zoster virus (VZV) in the aqueous humor in patients with herpes zoster ophthalmicus (HZO) and zoster sine herpete (ZSH). Methods: After informed consent was given, an aliquot of aqueous humor was collected from patients with VZV anterior uveitis (n = 8). Genomic DNA of the human herpes viruses was measured in the aqueous humor by two PCR assays: a qualitative multiplex PCR an...
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