Advances in TRP channel drug discovery: from target validation to clinical studies
Abstract
Transient receptor potential (TRP) channels are multifunctional signalling molecules with many roles in sensory perception and cellular physiology. Therefore, it is not surprising that TRP channels have been implicated in numerous diseases, including hereditary disorders caused by defects in genes encoding TRP channels (TRP channelopathies). Most TRP channels are located at the cell surface, which makes them generally accessible drug targets....
Paper Details
Title
Advances in TRP channel drug discovery: from target validation to clinical studies
Published Date
Sep 15, 2021
Volume
21
Issue
1
Pages
41 - 59
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