Prophage Tracer: precisely tracing prophages in prokaryotic genomes using overlapping split-read alignment
Abstract
The life cycle of temperate phages includes a lysogenic cycle stage when the phage integrates into the host genome and becomes a prophage. However, the identification of prophages that are highly divergent from known phages remains challenging. In this study, by taking advantage of the lysis-lysogeny switch of temperate phages, we designed Prophage Tracer, a tool for recognizing active prophages in prokaryotic genomes using short-read sequencing...
Paper Details
Title
Prophage Tracer: precisely tracing prophages in prokaryotic genomes using overlapping split-read alignment
Published Date
Sep 22, 2021
Journal
Volume
49
Issue
22
Pages
e128 - e128
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History