Antigenic Structural Similarity as a Predictor for Antibody Cross-Reactivity

Antibodies are an essential component of the adaptive immune system that function to neutralize foreign invaders, null such as bacterial and parasitic pathogens. However, B-cell epitopes remain difficult to predict due to their general null indistinguishability from other protein regions. Epitope prediction tools in the past have largely relied on amino acid null sequence similarity; however, implementing three-dimensional protein...