Model-based prediction of the moisture sorption kinetics and humidity-induced collapse for freeze–dried cakes
Abstract
Freeze–drying produces highly hygroscopic porous materials derived from ice microstructures. Because of this feature, moisture sorption over time during storage in contact with moist air, in the worst case, induces collapse. In this study, a mathematical model of the moisture sorption kinetics applicable to glassy freeze–dried matrices is developed. The model is based on the glass transition properties and sorption equilibrium data with a...
Paper Details
Title
Model-based prediction of the moisture sorption kinetics and humidity-induced collapse for freeze–dried cakes
Published Date
Feb 1, 2022
Journal
Volume
248
Pages
117129 - 117129
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